The constituents of the herb include over 60 Cannabinoids and 300 Terpenoids and some examples are:
CBD (CannaBiDiol), which has no affinity for any cannabinoid receptor known at this point, is of great medical value, anti-inflammatory, antispasmodic, analgesic and many more, but it's effect is seriously limited alone. This is why many studies have shown only minor medical benefit of this compound. Alone, anti-inflammatory action peaks at around 5mg/kg for a rat, and drops off in a bell shaped curve at higher doses. In conjunction with whole herb extracts the effect is no longer limited to the same bell-shaped curve but has a more linear dose-response relationship. However another action is as an antidote to THC, it lowers its psychoactive effects, specifically reducing anxiety, delusion and psychosis, without affecting many of it's therapeutic actions.
THC (TetraHydroCannabinol) is the psychoactive component everyone looks at as evil. It binds to both CB1 and CB2 cannabinoid receptors. CB1 are mostly localised to the nervous system. They are responsible for the psychoactive effect. They are also how it relieves alzheimer's, depression and nerve damage for example. CB2 receptors are found primarily in immune cells and some organs. These are those responsible for the pain-killing and anti-inflammatory properties of THC. More interestingly, Cancer cells have increased levels of CB2 receptors and 'THC has been shown to Kill Cancer' cells by this action.
CBG (CannaBiGerol) Has more powerful anti-spasmodic / anti-seizure / analgesic properties than either THC or CBD. It has been shown to have a potent anti-oxidant effect and to prevent the growth of cancer cells.
Limonene is a terpene which has stimulating and uplifting qualities for mood, and has anti-carcinogenic properties. It also promotes the absorption of cannabinoids across cellular barriers.
Myrcene is a terpene which has sedative, muscle relaxing, and pain killing properties. It also has the ability to increase the absorption of cannabinoids, by increasing the CB1 receptor's affinity for them.
This type of synergistic property is one of the greatest potentials of this herb, and must be able to be fully taken advantage of in the nature of products permitted.